1. What is ARIMIDEX and what is it used for?
Arimidex is White, round, biconvex film-coated tablet. The logo is printed on one side of the tablet and 1 is printed on the other.
The active ingredient of ARIMIDEX is anastrozole.
ARIMIDEX belongs to the group of medicines called aromatase inhibitors. This Medication blocks the effects of aromatase, an enzyme found in the body. The aromatase enzyme ensures the production of a female hormone called estrogen from the adrenal gland in women who have entered menopause. These female hormones have a stimulating effect on breast cancer. ARIMIDEX reduces the production of female hormones after menopause by inhibiting the effect of the aromatase enzyme.
ARIMIDEX is used to treat breast cancer in postmenopausal women. ARIMIDEX film-coated tablet is presented in a package containing 28 tablets.
3. How to use ARIMIDEX?
Instructions for proper use and dose/frequency of administration
Always strictly follow your doctor’s instructions when using ARIMIDEX. If you are unsure, ask your doctor or pharmacist.
The recommended dose for adults (including the elderly) is 1 tablet once a day.
Application route and method
• ARIMIDEX tablet is for oral use only.
• Swallow your tablets whole with some water.
• Try to take your medicine at the same times every day.
• Do not stop taking your tablets without telling your doctor, even if you feel well. Different age groups:
Use in children
Dose modification is not recommended in the elderly. It is used in the dose used in adults.
Special use cases
Kidney/Liver failure:
Do not use if you have severe kidney failure.
Do not use if you have moderate or severe hepatic impairment.
If you have the impression that the effect of ARIMIDEX is too strong or weak, talk to your doctor or pharmacist.
If you use more ARIMIDEX than you should
If you have used more of ARIMIDEX than you should, talk to a doctor or pharmacist immediately.
If you forget to use ARIMIDEX
Take the missed tablet as soon as you remember, but there should be at least 12 hours between it and the next dose. If there is less than 12 hours between the next dose, do not take the missed dose.
Continue your treatment by taking the next dose on time.
3. What are the possible side effects?
Like all medicines, there may be side effects in people who are sensitive to the substances contained in ARIMIDEX.
Side effects are listed as follows;
Very common: It can be seen in at least 1 in 10 patients.
Common: less than 1 in 10 patients, but more than 1 in 100 patients.
Uncommon: less than 1 in 100 patients, but more than 1 in 1000 patients. Rare: less than 1 in 1000 patients.
Very rare: less than 1 in 10,000 patients.
Unknown frequency: It can be seen in too few patients to be determined with the available data.
Very common side effects
• Headache,
• Hot flashes,
• Nausea,
• Hair thinning,
• Allergic reactions,
• Skin rash,
• Pain and stiffness in muscles and joints,
• Weakness, weakness
common side effects
• Anorexia,
• Elevation of cholesterol,
• Insomnia,
• Carpal tunnel syndrome (tingling, pain, coldness and weakness in some parts of the hand)
• Diarrhea,
• Vomiting,
• Increase in liver enzymes (alkaline phosphatase, alanine aminotransferase and aspartate aminotransferase),
• Vaginal dryness,
• Vaginal bleeding,
Uncommon side effects
• Increase in liver enzymes (gamma-Giuamyl transferase),
• Increase in bilirubin level,
• Jaundice,
• Skin rash such as urticaria,
rare side effects
• Lace-like redness on the hands, face and feet, which is called erythema multiforma, which usually disappears spontaneously,
• Serious allergic reactions
• Finger shape and usage disorder as a result of thickening of the connective tissue in the finger
Side effects with unknown frequency
• Very serious skin reactions called Stevens-Johnson syndrome, which are seen as tissue disorders in the skin in the form of inflamed wounds or blisters.
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