1. What is AROMASIN and what is it used for?
Aromasin Each coated tablet contains 25 mg of exemestane and is available in blister packs of 30 tablets.
They are round, biconvex, approximately 6 mm in diameter, gray white – slightly gray sugar-coated tablets, imprinted with “7663” in black ink on one side.
AROMASIN belongs to a group of medicines known as aromatase inhibitors. These drugs interact with a substance called aromatase, which is necessary for the production of sex hormones, estrogens, especially in postmenopausal women. Reducing estrogen levels in the body is one way to treat hormone-dependent breast cancer.
In patients with a special type of postmenopausal (Postmenopausal hormone receptor positive (estrogen and/or progesterone receptor)) early stage breast cancer, it is used for a period of 5 years, when the total hormonal treatment period is completed by switching to AROMASIN after 2-3 years of tamoxifen use.
It is used in the treatment of patients with a special type of postmenopausal (Postmenopausal hormone receptor positive (estrogen and/or progesterone receptor)) advanced breast cancer and in those with advanced disease after endocrine therapy.
2.How to use AROMASIN?
Always take your medicine exactly as your doctor has told you. If you are unsure, consult your doctor.
Instructions for proper use and dose/frequency of administration
• Your doctor determines the daily dose and duration of treatment.
• The recommended daily dose is 25 mg once.
Application route and method
• AROMASIN is taken orally.
• Doses should be taken after a meal, at approximately the same time each day.
different age groups
Use in children
Use in the elderly
Use in the elderly:
No dose adjustment is necessary.
Special use cases
No dose adjustment is necessary in patients with renal or hepatic impairment.
If you have the impression that the effect of AROMASIN is too strong or weak, talk to your doctor or pharmacist.
If you use more AROMASIN than you should
If you have accidentally taken too many tablets, contact your doctor or go to the nearest hospital emergency department. Show the box of AROMASIN tablets.
If you have used more than you should use from AROMASIN, talk to a doctor or pharmacist.
3. What are the possible side effects?
Like all medicines, there may be side effects in people who are sensitive to the substances contained in AROMASIN.
If any of the following occur, stop using AROMASIN and IMMEDIATELY inform your doctor or go to the nearest hospital emergency department.
• Hypersensitivity (such as edema on the face and/or lips, shortness of breath)
• Inflammation of the liver (hepatitis)
• Liver inflammation (cholestatic hepatitis) due to impaired excretion from the bile ducts, which causes yellowing of the skin.
If you generally do not feel well, feel nauseous, have yellowing of your skin and eyes (jaundice), itching, right-sided abdominal pain and loss of appetite, you may have one of the above side effects.
These are all very serious side effects. If you have one of these, you may need emergency medical attention or hospitalization.
AROMASIN is a well tolerated drug and the side effects that appear are usually mild or moderate. Many of the side effects are related to estrogen deficiency (eg hot flashes)
Listed below are all side effects by frequency of occurrence.
Side effects are classified as shown in the following categories:
: It can be seen in at least one of 10 patients.
Very rare Not known
: It can be seen less than one in 10 patients, but more than one in 100 patients.
: Less than one in 100 patients, but more than one in 1,000 patients.
: It can be seen less than one in 1,000 patients, but more than one in 10,000 patients.
: It can be seen in less than one of 10,000 patients.
: Cannot be estimated from the available data.
• State of mental depression (depression)
• Difficulty sleeping
• Hot flashes
• Feeling sick
• Increased sweating
• Muscle and joint pain (osteoarthritis, back pain, arthritis and stiffness in the joints)
• Decrease in white blood cells that defend the body against infections
• Stomach ache
• Elevated liver enzymes
• Increase in the level of destruction of oxygen-carrying cells (hemoglobin) in the blood
• Increased enzyme levels in the blood due to liver damage