1. What is Femara and what is it used for?
FEMARA tablets are dark yellow, round, slightly convex, film-coated tablets with bevelled edges, debossed with “FV” on one side and “CG” on the other side. Each film-coated tablet contains 2.5 mg of letrozole.
FEMARA is presented in blister packs containing 30 film-coated tablets.
Letrozole belongs to a group of medicines called aromatase inhibitors. Treatment with Femara is a hormonal (or “endocrine”) breast cancer treatment.
The development of breast cancer is often stimulated by estrogens, the female sex hormones. By blocking an enzyme (“aromatase”) that plays a role in estrogen production, FEMAR reduces the amount of estrogen and thus can prevent the growth of breast cancers that need estrogen in order to grow.
As a result, tumor cells slow or cease to progress and/or spread to other parts of the body. In addition, FEMARA can be used to reduce the size of the tumor before breast surgery, and it helps to prevent the recurrence of the tumor after breast surgery.
Monitoring of FEMARA therapy
Femara should only be taken under strict medical supervision.
Your doctor will check your condition regularly to check whether the treatment is having the desired effect.
Your doctor may also decide to monitor your bone health because this medicine can cause thinning or damage to bones (osteoporosis, osteoporosis).
If you have any questions about how Femara works or why this medicine has been prescribed for you, ask your doctor.
3.How to use FEMARA?
Instructions for proper use and dose/frequency of administration
• The generally used dose of FEMARA is 1 tablet once a day.
• Taking FEMARA at the same time every day will help you remember when to take your medicine.
• Always use FEMARA as your doctor has told you. If you are not sure how to use it, consult your doctor or pharmacist.
• Continue to use FEMARA as long as your doctor tells you. You may need to use FEMARA for months or years.
• If you have any questions about how long you will continue to use FEMARA , talk to your doctor.
Application route and method
• FEMARA is for oral use only.
• You can take the tablet on an empty stomach or on a full stomach.
• Swallow the tablets with a glass of water, preferably at the same time every day.
• Do not chew, split or crush the tablet.
Use in children
FEMARA is not for use in children or adolescents (under 18 years of age).
Use in the elderly
There is no specific dose recommendation for patients 65 years of age and older.
Special use cases
No dosage adjustment is necessary for patients with mild hepatic or renal impairment. However, patients with severe hepatic impairment should be kept under close surveillance.
Unless your doctor recommends otherwise follow these instructions. Do not forget to take your medicine on time.
Your doctor will tell you how long your treatment with Femara will last. Do not stop the treatment early, because you will not get the desired result.
If you have the impression that the effect of FEMARA is too strong or too weak, talk to your doctor or pharmacist.
If you use more FEMARA than you should
If you have used more than you should use from FEMARA , talk to a doctor or pharmacist.
You may need to seek medical treatment. Take the tablet box with you and show it to your doctor.
If you forget to use FEMARA
If you forget to take your medicine, take this dose as soon as you realize you forgot it and take the next dose at the usual time.
If you remember that you forgot to take your medicine very close to the time of the next dose (for example, 2 or 3 hours), skip the missed dose and take the next dose at the usual time.
Do not take a double dose to make up for forgotten doses.
4. What are the possible side effects?
Like all medicines, there may be side effects in people who are sensitive to the substances in the content of FEMARA .
The following side effects may occur as a result of using FEMARA :
If any of the following occur, stop using FEMARA and IMMEDIATELY inform your doctor or go to the nearest hospital emergency department:
• Arm or leg (extremities) or facial weakness or paralysis (paralysis), difficulty speaking (stroke symptoms),
• Chest pain that feels like tightness or sudden arm or leg (foot) pain (signs of a heart disease such as a heart attack),
• Swelling and redness in a vein that is extremely sensitive and painful to the touch [signs of blood clot formation due to inflammation of the veins (thrombophlebitis)],
• Difficulty breathing, chest pain, fainting, rapid heartbeat, bluish discoloration of the skin [signs of blood clot formation such as obstruction of the vessels in the lungs by a blood clot (pulmonary embolism)],
• Swelling in the arms, hands, feet, ankles or other parts of the body (signs of edema),