Hydrea 500 Mg 100 Caps Hydroxyurea

1. What is HYDREA and what is it used for?

HYDREA capsule is in the form of white powder in hard gelatin capsules consisting of two parts with a green cap and a pink opaque body imprinted with “BMS 300”.

HYDREA 500 mg Capsules is available in bottles of 100 capsules. There is one bottle in each box.

HYDREA is in a group of drugs called antineoplastics and used in the treatment of cancer.

HYDREA is used in the treatment of some cancer diseases such as cervical cancer, in the treatment of cancer of a type of blood cells called chronic myelocytic leukemia, and in the treatment of sickle cell anemia (a type of anemia).

Consult your doctor to learn more clearly why you are using HYDREA.

2.How to use HYDREA?

Instructions for proper use and dose/frequency of administration

Always use HYDREA as your doctor has told you. If you are not sure, consult your doctor or pharmacist.

The recommended dose should be calculated as 20-30 milligrams per kilogram of body weight once a day or 80 milligrams per kilogram of body weight every three days.

Sickle Cell Anemia:

The recommended dose is 15 milligrams per kilogram of body weight once a day.

Your doctor will decide on the starting dose of HYDREA based on your body weight and blood values. The dose can then be increased to the highest dose (the highest dose that does not cause a serious decrease in your blood values) to which you are able to withstand the effects of the drug.

After starting HYDREA treatment, your doctor will check your blood values at regular intervals. Depending on the results, your dose may be changed or HYDREA treatment may be interrupted for a while.

If you are receiving irradiation, you should take HYDREA 7 days before irradiation.

Application route and method

Take the capsules with a sufficient amount of water. If you cannot swallow the capsules, you can also take the capsule contents by pouring them into a glass of water and drinking immediately. Some fillers in the capsule may not dissolve in water and remain on the surface, do not worry about this. Do not inhale the capsule contents. If the dust comes into contact with your skin, wipe it off immediately.

Use in children

The safety and efficacy of HYDREA in patients under 18 years of age have not been established.
Use in the elderly

Elderly patients may be more sensitive to the effects of HYDREA and may need to use lower doses.

Special use cases

Kidney/Liver failure:

If you have kidney or liver failure, your doctor may reduce the starting dose of HYDREA and your blood values should be closely monitored.

If you have the impression that the effect of HYDREA is too strong or too weak, talk to your doctor or pharmacist.

If you use more HYDREA than you should

If you use more HYDREA than necessary, you should immediately contact your doctor or go to the nearest hospital. Show the box of your medicine.

If you have used more than you should use from HYDREA, talk to a doctor or pharmacist.

If you forget to use HYDREA

If you forget to use HYDREA

Keep taking your doses.

Do not take a double dose to make up for forgotten doses.

3. What are the possible side effects?

Like all medicines, there may be side effects in people who are sensitive to the substances contained in HYDREA.

If any of the following occur, stop using HYDREA and IMMEDIATELY inform your doctor or go to the nearest hospital emergency department:

– Remittance (watch)

– Skin cancer

– Unexpected difficulty in breathing or cough with fever These are all very serious side effects.

If you have one of these, you may need emergency medical attention or hospitalization.

All of these very serious side effects are very rare.

If you notice any of the following, tell your doctor immediately or go to the nearest hospital emergency department:

– Pain in the lower back or flank

– Black, dark stool or blood in the stool

– Abnormal bleeding or bruises

– Unexplained fever, chills or sore throat

– Numbness or tingling in hands or feet

– Skin ulcer, especially with severe inflammation

– Anemia

–  Hallucination (hearing, seeing or feeling things that are not there)

All these are serious side effects. Emergency medical attention may be required. Serious side effects are very rare.

Tell your doctor if you notice any of the following:

– Lack of appetite

– Weakness or loss of energy

– Nausea, vomiting, diarrhea

– Constipation, indigestion, digestive disorder

– Headache

–  Sleepiness, drowsiness

– the stupefaction

– Sores on the lip or mouth

– Temporary hair loss

– The rash

– Darkening of the skin color

– Skin and nail loss

– Purple injuries or peeling of the skin

– Stomach ache

– The problem of adaptation to the environment (disorientation)

– tremor

– Reddening of the skin after radiation therapy

– Difficult or painful urination

These are mild side effects of HYDREA.