1. What is INVEGA and what is it used for?
• Each of INVEGA 9 mg extended-release tablets contains 9 mg paliperidone.
• INVEGA belongs to a group of drugs known as antipsychotics.
• INVEGA is available in the form of 28 tablets.
• INVEGA is prescribed for the treatment of schizophrenia.
• INVEGA is prescribed for the treatment of schizoaffective disorder (a type of psychiatric disease defined by the periodic recurrence of mood and mental balance disorders) alone or in combination with drugs and/or mood stabilizers effective against depression/mental depression.
2. How to use INVEGA?
Instructions for proper use and dose/frequency of administration
• Your doctor will tell you how long your treatment with INVEGA will last and at what dose and how many tablets you should take. Always follow your doctor’s recommendations exactly.
• If you are not sure about how to take INVEGA, consult your doctor.
Application route and method
• You can take INVEGA with breakfast or on an empty stomach in the morning. However, make sure to take INVEGA in the same way every morning.
• Take INVEGA orally, swallow it whole with a sufficient amount of liquid (eg with a glass of water). Do not chew, break or crush the tablets.
• Sometimes, the tablet shell can be seen in the stool. This is a normal situation.
• Your doctor will let you know how long your treatment with INVEGA will last. Even if you feel that you are getting better, do not interrupt your treatment.
• Do not forget to take your medicine on time.
Use in children
The safety and efficacy of INVEGA in patients under 18 years of age have not been studied and its use is not recommended.
Use in the elderly
Since renal function may decrease in elderly patients, dose adjustment may be required according to renal function status.
Special use cases
• In patients with mild renal impairment (creatinine clearance > 50 to <80 ml/min), the recommended starting dose is 3 mg once a day. The dose may be increased to 6 mg daily based on clinical response and tolerability.
Use in the elderly
Use in the elderly
If you have the impression that the effect of INVEGA is too strong or too weak, talk to your doctor or pharmacist.
If you use more INVEGA than you should
If you have used more than you should use from INVEGA, talk to a doctor or pharmacist.
This may cause drowsiness, drowsiness, lightheadedness from low blood pressure, and an abnormal heartbeat.
3. What are the possible side effects?
Like all medicines, there may be side effects in people who are sensitive to the substances contained in INVEGA.
If any of the following occur, stop using INVEGA and IMMEDIATELY inform your doctor or go to the nearest hospital emergency department:
• Swelling of the mouth, face, lips, tongue or throat
• Doughness of breath
• Rash, raised rash, itching
These are all very serious side effects. If you have any of these, you have a serious allergy to INVEGA. You may need emergency medical attention or hospitalization.
All of these very serious side effects are very rare.
If you notice any of the following, tell your doctor immediately or go to the nearest hospital emergency department:
• Changes in your heartbeat; eg change in heart rate, change in heart rhythm, palpitations, slow heart rate
• Imbalance in your blood pressure; eg low blood pressure, low blood pressure when standing up from a sitting or lying position
• Blur in vision, involuntary abnormal movements of the eyelids (oculogic crisis)
• Pain while urinating, burning (may be a sign of urinary system infection)
• Cerebral vascular event (cerebrovascular accident), convulsion, a kind of reversible paralysis resulting from temporary blockage of the vessels leading to the brain, fainting, impaired voluntary movements, slowing of voluntary movements, speech or language disorders (dysarthria), weakness, mouth, involuntary movements of limbs such as tongue, arms and legs (tardive dyskinesia)
• Irregularity in EKG (recording of electrical activity of the heart) results
• Pulmonary inflammation (aspiration pneumonia) that develops as a result of the escape of gastric contents into the respiratory tract
• The condition of blood clotting in the veins, especially in the legs, that moves from the blood vessels to the lungs, causing chest pain and difficulty in breathing (including symptoms such as swelling, pain and redness in the legs)
All these are serious side effects. Emergency medical attention may be required. Serious side effects are very rare.
Tell your doctor if you notice any of the following:
• Inflammation of the nose and pharynx (nasopharyngitis)
• Headache, dizziness, sleepiness, restlessness, tremor, calming (sedation)
• Upper respiratory tract infection, inflammation of the nasal mucosa (flu, rhinitis)